The purpose of this paper is to expose the function of the culture and thought of the Far East, expressed in Japanese Zen Buddhism and Chinese Chan (as well as, in general, in Chinese philosophy and culture), within the thought of Byung-Chul Han. This dimension of the Korean's work has not been sufficiently deepened in the analyses that are made of him. This error leads to mistakes such as stating that there is no emancipation proposal in Han or that his (...) work is limited to a pessimistic description of the world. Thus, the investigation that follows the bibliographic-documental research method is divided into three moments; the first exposes the foundations of the philosophy of Zen-chan Buddhism developed by Han; the second delineates the ontology of Hanian falsification and; the third, analyzes the theses on the East within Han's theoretical project. (shrink)

Extending the relation between semi-Heyting algebras and semi-Nelson algebras to dually hemimorphic semi-Heyting algebras, we introduce and study the variety of dually hemimorphic semi-Nelson algebras and some of its subvarieties. In particular, we prove that the category of dually hemimorphic semi-Heyting algebras is equivalent to the category of dually hemimorphic centered semi-Nelson algebras. We also study the lattice of congruences of a dually hemimorphic semi-Nelson algebra through some of its deductive systems.

The use of visual attention for evaluating consumer behavior has become a relevant field in recent years, allowing researchers to understand the decision-making processes beyond classical self-reports. In our research, we focused on using eye-tracking as a method to understand consumer preferences in children. Twenty-eight subjects with ages between seven and twelve years participated in the experiment. Participants were involved in two consecutive phases. The initial phase consisted of the visualization of a set of stimuli for decision-making in an eight-position (...) layout called Alternative Forced-choice. Then the subjects were asked to freely analyze the set of stimuli, they needed to choose the best in terms of preference. The sample was randomly divided into two groups balanced by gender. One group visualized a set of icons and the other a set of toys. The final phase was an independent assessment of each stimulus viewed in the initial phase in terms of liking/disliking using a 7-point Likert scale. Sixty-four stimuli were designed for each of the groups. The visual attention was measured using a non-obstructive eye-tracking device. The results revealed two novel insights. Firstly, the time of fixation during the last 4 visits to each stimulus before the decision-making instant allows us to recognize the icon or toy chosen from the eight alternatives with a 71.2% and 67.2% of accuracy respectively. The result supports the use of visual attention measurements as an implicit tool to analyze decision-making and preferences in children. Secondly, eye movement and the choice of liking/disliking choice are influenced by stimuli design dimensions. The icon observation results revealed how gender samples have different fixation and different visit times which depend on stimuli design dimension. The toy observations results revealed how the materials determinate the largest amount fixations, also, the visit times were differentiated by gender. This research presents a relevant empirical data to understand the decision-making phenomenon by analyzing eye movement behavior. The presented method can be applied to recognize the choice likelihood between several alternatives. Finally, children's opinions represent an extra difficulty judgment to be determined, and the eye-tracking technique seen as an implicit measure to tackle it. (shrink)

Bibliografía seleccionada y comentada sobre Taoísmo Clásico : Dao De Jing.

En este trabajo se estudia la virtud de la confianza como requisito de la sociabilidad. Tras revisar, en síntesis y según L. Polo, como se ha estimado esta virtud en la historia de la filosofía, y tras examinar algunas manifestaciones del vicio opuesto de la desconfianza, se indica cuál es su índole, su raíz y sus consecuencias, distinguiéndola al final de la fe intelectual o natural que tiene como tema solo a Dios.

An integral subresiduated lattice ordered commutative monoid (or integral srl-monoid for short) is a pair \(({\textbf {A}},Q)\) where \({\textbf {A}}=(A,\wedge,\vee,\cdot,1)\) is a lattice ordered commutative monoid, 1 is the greatest element of the lattice \((A,\wedge,\vee )\) and _Q_ is a subalgebra of _A_ such that for each \(a,b\in A\) the set \(\{q \in Q: a \cdot q \le b\}\) has maximum, which will be denoted by \(a\rightarrow b\). The integral srl-monoids can be regarded as algebras \((A,\wedge,\vee,\cdot,\rightarrow,1)\) of type (2, 2, (...) 2, 2, 0). Furthermore, this class of algebras is a variety which properly contains the varieties of integral commutative residuated lattices and subresiduated lattices respectively. In this paper we study the quasivariety of \(\{\wedge,\cdot,\rightarrow,1\}\) -subreducts of integral srl-monoids, which will be denoted by \(\mathsf {SR^s}\). In particular, we show that \(\mathsf {SR^s}\) is a variety. We also characterize simple and subdirectly irreducible algebras of \(\mathsf {SR^s}\) respectively. Finally, through a Hilbert style system, we present a logic which has as algebraic semantics the variety \(\mathsf {SR^s}\) and we apply this result in order to present an expansion of the previous logic which has as algebraic semantics the variety of integral srl-monoids. (shrink)

Empirical research on Rational Choice Theory has brought up two focus of the economics laws problem. On one hand, we find the authors who state that the neoclassical economics laws are explanatory and predictive on specific cases: in transparent contexts in which the standard rationality operates successfully. On the other hand, we find the authors who state that the descriptive theories of the rational choice opens up a research path in which fundamental principles of the neoclassical building could be questioned. (...) Both view points have generated an important standard Rational Choice Theory revision what has produced the so called descriptive view point. It implies understanding that most of the choices take place under risky or uncertainty conditions and, that, these choices are far more complex than the normative Rational Choice Theory supposes. This article's main goal is to expand the descriptive point of view in rational choice, theorizing how some factors, coming from the social and cultural environment, operate within the rational choice. Into space of this research essay we find the debatable question of whether these sort of proposals expands the explanation of the deviation of the rational choice normative theory, and that, of the disturbing causes of the microeconomics laws, or they call into question fundamental principles of these laws and therefore they are opening the possibility to focus some economics issues in a new different manner. (shrink)

We study experimentally in the laboratory the situation when individuals have to report their private information about a variable to a public authority that then makes inference about the true values given a known variable using a regression technique. It is assumed that individuals prefer this predicted value to be as close as possible to their true value. Consistent with the theoretical literature, we show that subjects misrepresent their private information more when an ordinary least squares regression is implemented than (...) when the so-called resistant line estimator is employed. The latter extends the median voter theorem to the two-dimensional setting and belongs to the family of robust estimation techniques. In fact, we find that OLS involves serious biases but the RL estimation is empirically unbiased. Furthermore, subjects never earn less when the RL is applied. (shrink)

In the second half of the 20th century, Latin American poetry has had to deal with representing the phenomenon of forced disappearance in its various poetic productions. Some of those have incubated in the Central American civil wars, the dictatorial regimes of the Southern Cone and even in countries with supposed democratic stability such as Mexico and Colombia. Memorial de Ayotzinapa, by the Mexican poet Mario Bojórquez, and Carta de las mujeres de este país, by the Colombian poet and activist (...) Fredy Yezzed, experiment with the discursive forms of the long poem and the letter poem, respectively, to construct collective memories around a phenomenon that continues to take lives to this day. Bojórquez's text is concerned with constructing a testimony, apparently in situ, of the disappearance of the forty-three Mexican teacher trainees; Yezzed's work, for its part, refrains from referring to a specific event or place in order to provide a more complete testimony of the Colombian armed conflict, nearly seventy years old. The article analyzes the forms of the text, the subjects and their spaces of enunciation, as well as the memory strategies that are seen in both works. Thus, the testimonial status of poetry is confirmed, sometimes overshadowed by genres such as the novel and the short story. (shrink)

Este artículo distingue entre creatividad e innovación, asume el enfoque sistémico en estudios de innovación y lo aplica a las innovaciones poéticas y literarias. Se centra en sor Juana Inés de la Cruz, la gran poeta y escritora del virreinato español en México a finales del siglo XVII. Sor Juana vinculó las artes literarias con las ciencias y técnicas de la época barroca y consiguió apoyos sociales, políticos y religiosos que la convirtieron en una mujer emprendedora y altamente innovadora. También (...) se analiza el resurgimiento de la figura de sor Juana en el siglo XX, gracias a escritores como Amado Nervo, Clara Campoamor y Octavio Paz, así como a investigadores mexicanos e internacionales que han generado una gran innovación social, cultural e institucional, el sorjuanismo, cuyos hitos principales se analizan. (shrink)

Risk taking is a component of the decision-making process in situations that involve uncertainty and in which the probability of each outcome – rewards and/or negative consequences – is already known. The influence of cognitive and emotional processes in decision making may affect how risky situations are addressed. First, inaccurate assessments of situations may constitute a perceptual bias in decision making, which might influence RT. Second, there seems to be consensus that a proneness bias exists, known as risk proneness, which (...) can be defined as the propensity to be attracted to potentially risky activities. In the present study, we take the approach that risk perception and risk proneness affect RT behaviours. The study hypothesises that locus of control, emotion regulation, and executive control act as perceptual biases in RT, and that personality, sensation seeking, and impulsivity traits act as proneness biases in RT. The results suggest that locus of control, emotion regulation and executive control influence certain domains of RT, while personality influences in all domains except the recreational, and sensation seeking and impulsivity are involved in all domains of RT. The results of the study constitute a foundation upon which to build in this research area and can contribute to the increased understanding of human behaviour in risky situations. (shrink)

En este texto se hace una introducción y una breve presentación de las distintas contribuciones al dossier. Específicamente, en el texto se precisan los distintos sentidos y perspectivas en los que se han planteado reflexiones filosóficas sobre los distintos aspectos de la educación en América Latina, se muestran algunas líneas temáticas de las reflexiones, se relacionan esas reflexiones con algunos de los planteamientos de la filosofía latinoamericana, se justifica la importancia de continuar y fomentar el trabajo filosófico en este amplio (...) terreno de reflexión filosófica, y se plantean algunos retos para las futuras reflexiones. Finalmente, se presentan y comentan los artículos que forman parte del dossier. (shrink)

El objetivo de este trabajo fue calcular la proporción global de ansiedad de estudiantes de medicina durante la pandemia de COVID-19. Se realizó una búsqueda sistemática de artículos publicados hasta el 6 de enero de 2021 en Medline que reportaran prevalencia de ansiedad (según GAD-7) en estudiantes de medicina durante la pandemia de COVID-19. Diez estudios fueron incluidos en el meta-análisis, arrojando una prevalencia global estimada de ansiedad en estudiantes de medicina del 42. Este hallazgo sugiere la necesidad de evaluar (...) sintomatología ansiosa entre los estudiantes de medicina durante la pandemia de COVID-19 y establecer programas de apoyo psicológico adecuados. (shrink)

This paper examines the influence of internal barriers on the relationship between the organizational capability of stakeholder integration and proactive environmental strategies. We adopt a moderate hierarchical regression model to test the hypotheses using data from a sample of 73 managers in the business education industry. The paper contributes to stakeholder theory by showing that stakeholder integration positively influences the development of proactive environmental strategies when managers perceive internal barriers to the development of such strategies. This article also explores an (...) ethical dilemma—managers may use the stakeholder integration capability to support their own interests rather than to benefit stakeholders. (shrink)

In recent years it has been demonstrated that the use of the traditional property registry models involves the risk of corruption along with long waiting times. This paper points out the main problems associated with conventional models and makes a survey of the new ones that are based on blockchain technology. This type of model is already being developed as a proof of concept by different countries. With the use of this technology in land registry systems, it is possible to (...) improve the transparency of the processes as well as optimize costs and execution time. To show the theoretical results of this study, the Spanish land registry has been taken as an example of a use case scenario. (shrink)

Este artículo tiene por objetivo retomar la teoría de Byung Chul Han sobre la sociedad del logro (Leistungsgesellschaft), tomando específicamente lo expuesto por él sobre el dogma de la transparencia que surge en la lógica neoliberal-digital contemporánea, para ser completado con la teoría freudiana de lo Unerkante -no reconocible-. Para esto el trabajo se divide en tres momentos: el primero tiene por objetivo exponer lo que se entiende por dogma de la transparencia y cómo se relaciona con el Homo œconomicus; (...) seguidamente, se presenta el concepto de lo Unerkante de Freud para plantear una nueva topología de lo no-reconocible en el plano subjetivo, proponiendo el concepto del ombligo de la subjetividad; y, finalmente, se expone cómo ese ombligo empalma con la teoría de Han frente a la transparencia, de modo que se puedan generar nuevas interpretaciones de lo que sería una salida a la sociedad del logro. (shrink)

Background: Heart rate variability (HRV) has been considered as a measure of heart-brain interaction and autonomic modulation, and it is modified by cognitive and attentional tasks. In cognitive tasks, HRV was reduced in participants who achieved worse results. This could indicate the possibility of HRV predicting cognitive performance, but this association is still unclear in a high cognitive load sport such as chess Objective: To analyse modifications on HRV and subjective perception of stress, difficulty and complexity in different chess problem (...) tasks. Design: HRV was assessed at baseline. During the chess problems, HRV was also monitored, and immediately after chess problems the subjective stress, difficulty and complexity were also registered. Method: A total of 16 male chess players, age: 35.19 (13.44) and ELO: 1927.69 (167.78) were analysed while six chess problem solving tasks with different level of difficulty were conducted (two low level, two medium level and two high level chess problems). Participants were classified according to their results into two groups: high performance or low performance. Results: Friedman test showed a significant effect of tasks in HRV indexes and perceived difficulty, stress and complexity in both high and low performance groups. A decrease in HRV was observed in both groups when chess problems difficulty increased. In addition, HRV was significantly higher in the high performance group than in the low performance group during chess problems. Conclusions: An increase in autonomic modulation was observed to meet the cognitive demands of the problems, being higher while the difficulty of the tasks increased. Non-linear HRV indexes seem to be more reactive to tasks difficulty, being an interesting and useful tool in chess training. (shrink)

El correcto mantenimiento de las zonas donde se alojan los perros y el uso de repelentes es fundamental para la prevención de la transmisión de esta enfermedad.

La presente investigación expone las alternativas subjetivas que pueden acontecer en el marco del capitalismo contemporáneo desde la mirada filosófica de Byung-Chul Han. Para ello, se recurre a tres momentos: el primero, describe la actual sociedad neoliberal en el marco de la pospandemia; el segundo, trabaja el concepto de tiburón del rendimiento como una figura hegemónica en la dominación sistémica del sujeto; y, finalmente, se expone el concepto de homini cochlea como una alternativa no hegemónica de resistir a estos mecanismos (...) y dispositivos subjetivos que buscan mantener la reproducción del neoliberalismo. Toda esta reflexión sobre los modos de comprender la producción de subjetividad parte de una interpretación del pensamiento de Byung-Chul Han a la vez que se enmarca su filosofía en los debates contemporáneos frente a los modos de control del neoliberalismo, por lo que las mayorías de las directrices filosóficas, en este manuscrito, siguen su forma de comprender el mundo y el modo en que esta converge con otros pensadores. (shrink)

On many occasions, the maximum result of a team does not equate to the total maximum individual effort of each athlete (social loafing). Athletes often combine their sports life with an academic one (Dual Career), prioritizing one over the over in a difficult balancing act. The aim of this research is to examine the existence of social loafing in a group of novice university rowers and the differences that exist according to sex, academic performance, and the kind of sport previously (...) practiced (individual or team). Therefore, a study was conducted from a probabilistic perspective using the Bayesian Network analysis methodology. The results confirm the existence of the Ringelmann effect or social loafing. The Bayesian analysis let us confirm that having a good student who practices a team sport, even in the individual rowing concept, increases the probability of obtaining greater performance (higher number of strokes and more power in each one). Therefore, when rowing partnerships are formed, the occurrence probability chain is quickly simplified, along with values of the top and bottom variables. Finally, the instantiations undertaken on the bottom variable that appears to be common in the two BNs, the watt input, enhance the results obtained. In short, rowers who have a better academic record are more involved in team testing, so this characteristic is defining when it comes to achieving better performance in team testing. (shrink)

The Coronavirus Disease 2019 pandemic, now a global health crisis, has surprised health authorities around the world. Recent studies suggest that the measures taken to curb the spread of the COVID-19 outbreak have generated issues throughout the population. Thus, it is necessary to establish and identify the possible risk factors related to the psychosocial and psychophysiological strain during the COVID-19 outbreak. The present extensive literature review assesses the social, psychological, and physiological consequences of COVID-19, reviewing the impact of quarantine measures, (...) isolation, vast human loss, social and financial consequences in the family’s economies, and its impact on the psychological health of the population. We also discussed the effect of psychophysiological factors, considering the impact of physical inactivity and modifications in nutritional habits, at psychological and physiological levels. The present review includes an actualized to date bibliography, articles for which were methodologically analyzed to verify they met the standards of quality and scientific accuracy. Authors understand the pandemic as a multifactorial event for which only a profound and extensive analysis would lead to better compression and efficient intervention in the near future. (shrink)

In this article are treated, in general strokes, the methodological foundations of the Diccionario de conceptos políticos y sociales de la España de los siglos XIX y XX which has been published recently under the direction of the above mentioned editors. This dictionary in which nearly 200 authors of different Spanish universities and centres of research have collaborated collects more than 100 articles. It is partly inspired by the German Begriffsgeschichte. Its editors, however, have also taken into account the contribution (...) of the famous school of Cambridge by adapting the influences of several methodological currents to the specific claims of their work, i. e. to the elaboration of a dictionary which, on the basis of a huge volume of sources, pretends to cartograph, in an alphabetical order, the principal ideological lines – the discoursive and conceptual ones – of the Spanish 19th century. The article ends with a discussion of certain difficulties and aspects which are treated controversally in the intellectual history. It also claims to give a reflexion on the suitability and meaning which can – in the actual situation of the social sciences – pretend to determine the studies of political languages, especially the basic essays concerning the comparative history of political and social thinking under a conceptual perspective. (shrink)

The question of whether the entrepreneur is born or made, forces us to respond that the entrepreneurial culture clearly breaks with the myth that entrepreneurs are born. Currently, it is considered that entrepreneurial skills can be acquired like any other discipline and that is why it should be taught. Their teaching and learning are key to the well-being of the teacher and to the positive achievement of the students. The entrepreneurial culture is an educational objective of developed societies and has (...) its origin in the business culture. There are two current models, American and European. The one that develops in the Extremadura region, based on the European model, tries to create a vital state in the participating students that enhances competences such as creativity, personal initiative or self-confidence, elements that try to generate a true motivation to undertake. The motivated, accomplished and positive teacher contributes to that achievement and achieving it favors the well-being of teachers. It’s a round trip. It is a “do ut des.” In our research, we evaluated four entrepreneurial culture programs in the classroom: “Junioremprende,” “Teenemprende,” “Experemprende,” and “Youthemprende.” The teachers involved in the programs are 356, and the valid questionnaires are 154. The students enrolled in the programs are 4800, and the questionnaires valid 1198. In the questionnaire, one of the key questions is “general teacher satisfaction,” with 17 common questions for all the programs. An essential question posed is: “I am satisfied with the achievements obtained by my students to participate in the program” The results of our research, according to a seven-point Likert scale, gives a very high degree of teachers’ satisfaction. Their satisfaction was centered on the perception of their teachings are conducive to the achievement of his students. The degree of teacher satisfaction for each of the programs and significantly means differences were found with Junior program resulted the more satisfied for teachers. For students, participation in the programs resulted in high development of entrepreneurial competencies. Similarly to teachers results, Junior program was found more significant in developing students’ entrepreneurial competencies indicating that entrepreneurial education is very appropriate for children. Findings of this study suggest that entrepreneurial education should be encouraged for students at every stage of education. (shrink)

The aim of the present study was to assess the impact of past traumatic war experiences on preadolescents in the Gaza Strip, which could be useful for psychological intervention with current and future child victims. Participants were 521 preadolescents from United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) schools, aged 11 and 13 years old. Sections I to IV from Iraqi Version-Arabic of Harvard Trauma Questionnaire was used to assess trauma experiences and Post-Traumatic Stress (...) Disorder (PTSD). The results show that the preadolescents in the Gaza Strip witnessed the destruction of their homes and the murder of family members and friends. A quarter of the individuals assessed either suffered torture or witnessed others undergoing it, including sexual assaults. Almost half of them experienced a lack of food and clean water. The traumatic and torture experiences seriously affected preadolescents’ mental health as 26.29% met criteria for the diagnosis of PTSD. The data analysis revealed two PTSD modalities, with the severity of impact depending on whether social implications were involved. Further research is required to check whether these two modalities fit to PTSD and complex PTSD. Understanding the effects of past wars on preadolescents in Gaza and distinguishing between different PTSD types could enhance comprehension of the impacts of current attacks on child victims. It can also aid in determining the type of intervention needed to minimize the impact on the mental health of Palestinian youth, enhancing their resilience through psychological and social support. (shrink)

The objective of this research is to develop accurate forecasting models for chlorophyll-α concentrations at various depths in El Mar Menor, Spain. Chlorophyll-α plays a crucial role in assessing eutrophication in this vulnerable ecosystem. To achieve this objective, various deep learning forecasting techniques, including long short-term memory, bidirectional long short-term memory and gated recurrent uni networks, were utilized. The models were designed to forecast the chlorophyll-α levels with a 2-week prediction horizon. To enhance the models’ accuracy, a sliding window method (...) combined with a blocked cross-validation procedure for time series was also applied to these techniques. Two input strategies were also tested in this approach: using only chlorophyll-α time series and incorporating exogenous variables. The proposed approach significantly improved the accuracy of the predictive models, no matter the forecasting technique employed. Results were remarkable, with |$\overline{\sigma}$| values reaching approximately 0.90 for the 0.5-m depth level and 0.80 for deeper levels. The proposed forecasting models and methodologies have great potential for predicting eutrophication episodes and acting as decision-making tools for environmental agencies. Accurate prediction of eutrophication episodes through these models could allow for proactive measures to be implemented, resulting in improved environmental management and the preservation of the ecosystem. (shrink)

This article explores how historical narratives affect the evaluation of political decisions regarding justice during peace negotiations. Specifically, this study evaluates how different narratives of the Colombian armed conflict relate to the preference for either restorative or retributive justice. Results revealed that a historically accurate narrative that included structural elements correlated with the preference for restorative justice, whereas a schematic narrative that focused on individual greed favoured the preference for retributive justice. These results are explained in terms of the characteristics (...) of expert historical narratives, which include structural elements, such as economic and institutional factors. The presence of these elements in the explanation of conflicts decreases the weight of individual decisions and, in this way, prevent ingroup attributional biases. (shrink)

With the advent of the cloud computing model allowing a shared access to massive computing facilities, a surging demand emerges for the protection of the intellectual property tied to the programs executed on these uncontrolled systems. If novel paradigm as confidential computing aims at protecting the data manipulated during the execution, obfuscating techniques (in particular at the source code level) remain a popular solution to conceal the purpose of a program or its logic without altering its functionality, thus preventing reverse-engineering (...) on the program even with the help of computing resources. The many advantages of code obfuscation, together with its low cost, makes it a popular technique. This paper proposes a novel methodology for source code obfuscation that can be used together with other traditional obfuscation techniques, making the code more robust against reverse engineering attacks. Three program complexity metrics are used to define three different single-objective combinatorial optimization versions of the problem, which are solved and analysed. Additionally, three multi-objective problems are defined, those considering each of the selected metrics together with the program execution time, in order to avoid strong obfuscations penalizing the performance. The goal of the defined problems is to find sequences of LLVM optimizations that lead to highly obfuscated versions of the original code. These transformations are applied to the back-end pseudo-assembly code (i.e., LLVM Intermediate Representation), thus avoiding any further optimizations by the compiler. Classical genetic algorithms (GAs) are used to solve the studied problems, namely a basic cellular GA for the single-objective problems and the popular NSGA-II for the multi-objective ones. The promising results show the potential of the proposed technique. (shrink)

El presente escrito tiene por objetivo demostrar cómo el estado actual del capitalismo neoliberal, entendido como una fuerza productora de la subjetividad basada en el rendimiento [síntesis de la disciplina (Foucault) y el control (Deleuze y Guattari) que se cataliza con la digitalidad (Han, Berardi, Fisher, entre otros)], se centra en ejercer una colonización frente al tiempo como concepto estructural de la existencia humana para poder desplegar un sistema de dispositivos psicopolíticos que le permitan su reproducción sistémica. Para conseguir este (...) objetivo la investigación cuenta con tres momentos: el primero expone el paso del domino espacial del capitalismo fordista al neoliberalismo actual de carácter temporal desde una disincronía del tiempo. El segundo explica la desfactificación del mundo como la pérdida del vínculo humano con la realidad, lo que perturba directamente el estado de ánimo de los sujetos desde un peso cargado de nihilismo. Finalmente, se expone la psicopolítica como un concepto que parte tanto de la disincronía como de la desfactificación para posicionar un dominio sugestivo de la psique humana. (shrink)

The emergent Coronavirus Disease 2019 caused by the Severe Acute Respiratory Syndrome Coronavirus 2 could produce a maternal immune activation via the inflammatory response during gestation that may impair fetal neurodevelopment and lead to postnatal and adulthood mental illness and behavioral dysfunctions. However, so far, limited evidence exists regarding long-term physiological, immunological, and neurodevelopmental modifications produced by the SARS-CoV-2 in the human maternal-fetal binomial and, particularly, in the offspring. Relevant findings derived from epidemiological and preclinical models show that a MIA (...) is indeed linked to an increased risk of neurodevelopmental disorders in the offspring. We hypothesize that a gestational infection triggered by SARS-CoV-2 increases the risks leading to neurodevelopmental disorders of the newborn, which can affect childhood and the long-term quality of life. In particular, disruption of either the maternal or the fetal cholinergic anti-inflammatory pathway could cause or exacerbate the severity of COVID-19 in the maternal-fetal binomial. From a translational perspective, in this paper, we discuss the possible manifestation of a MIA by SARS-CoV-2 and the subsequent neurodevelopmental disorders considering the role of the fetal-maternal cytokine cross-talk and the CAP. Specifically, we highlight the urgent need of preclinical studies as well as multicenter and international databanks of maternal-fetal psychophysiological data obtained pre-, during, and post-infection by SARS-CoV-2 from pregnant women and their offspring. (shrink)

Lo que aquí presentamos es una pequeña introducción a un libro sobre el Fórum. Nos hacemos eco, siquiera someramente, de las polémicas que giraron en torno al evento, prácticamente desde su origen, trascendiéndolas en cambio para dar pie a una reflexión ¿que es justo lo que pretendíamos en ese libro- sobre nuestra sociedad en su conjunto. Conviene advertir que las contradicciones y paradojas del acontecimiento nos parecieron deudoras de las que sufre al mismo tiempo el mundo actual. En esa pequeña (...) introducción, y al hilo de tales consideraciones, concluimos con unas palabras dirigidas al filósofo, o al intelectual en general, que vienen a servir menos como un intento de crítica o de advertencia que como una declaración de intenciones de los miembros que componen el Seminario de Filosofía Política, en cuyo seno se gestó la obra. (shrink)